Cyclic coordinate descent: A robotics algorithm for protein loop closure

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چکیده

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Cyclic coordinate descent: A robotics algorithm for protein loop closure.

In protein structure prediction, it is often the case that a protein segment must be adjusted to connect two fixed segments. This occurs during loop structure prediction in homology modeling as well as in ab initio structure prediction. Several algorithms for this purpose are based on the inverse Jacobian of the distance constraints with respect to dihedral angle degrees of freedom. These algor...

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ژورنال

عنوان ژورنال: Protein Science

سال: 2003

ISSN: 0961-8368,1469-896X

DOI: 10.1110/ps.0242703